In vivo local transcranial static magnetic field stimulation alters motor behavior in normal rats

Transcranial static magnetic field stimulation (tSMS) has inhibitory neuromodulatory effects on the human brain. Most of studies fields have been performed in vitro. To further understand biological mechanisms tSMS, we investigated vivo tSMS motor behavior normal awake rats. The skull a male Wistar rat was exposed and polyethylene tube attached to using dental cement at center cortex (n = 7) or other 6). By attaching cylindrical NdFeB neodymium magnet into tube, (REAL) performed. For SHAM, applied similar size non-magnetic stainless-steel cylinder. All rats received twice each SHAM REAL every two days crossover design, function measured during stimulation. Activity level asymmetry forelimb use were not affected, but less accurate movements horizontal ladder test found cortex. This study shows that depending stimulated region